1924-жылдын 3-март күнү Англиянын ишенимдүү малайы Мустафа Камал Ататүрктүн колу менен Ислам мамлекети кулатылгандан бери мусулмандардын башынан баскынчылык, колония кылуу, талап-тоноо жана массалык кыргын кылуулар кетпей жатат. Айрыкча, бүгүнкү күнгө келип Борбордук Африка республикасы жана Бирма сыяктуу мамлекеттерде бардыгынын көз алдында мусулмандарды массалык кыргын кылуу, муслималардын намысына кол салуу барган сайын күчөп бара жатат.
Ошол себептен улам, Түркия вилаятындагы Хизбут-Тахрир жигиттери 90 жыл мурда кулатылган Халифалык мамлекетин жаңыдан турмушка кайтаруу максатында бир демилгени көтөрүп чыгышты.
Калыс Аллах үчүн бел байлаган бул жигиттер “Халифалыкты турмушка кайтаруу жумалыгы” деп аталган кампанияны башташты. Ушул демилге жыйындар, конференциялар жана бардык социалдык тармактар аркылуу “Халифалык – Үммөттүн негизги маселеси” экендигин бүтүндөй мусулмандарга дагы бир жолу эскертип өтүү максатында ишке ашырылууда.
Алардын урааны төмөнкүдөй: Жан дилибиз менен аракет кылуу бизден, натыйжа болсо Аллах Тааладан.
“Халифалыкты турмушка кайтаруу жумалыгы” кампаниясы 24-февралда башталды, Инша Аллах, 3-мартка чейин уланат.
Ушундай максатта Хизбут-Тахрирге таандык аялдар Түркиянын Стамбул шаарында конференция өткөрүүнү жарыя кылышты. Бул конференцияга бардык мусулималарды чакырат.
Адрес: Стамбул шаары, Жам Чешме кварталы, Кемел Паша көчөсү №25.
Конференция убагы: 27-март, 2014-ж. Саат 13:30.
Туркистон:
Боордошторубуздун демилгесине Аллах ыраазы болсун жана нусрат берсин. Чындыгында куфр дүйнөсү жогоруда көрсөтүлгөн Исламий аймактарда мусулмандарга карата чыныгы геноцидди ишке ашырууда. Алар мусулмандардын чачыранды абалынан пайдаланышып, ал тургай бири-бирине каршы коюуга аракет кылышууда.
Бүгүнкү күндө мусулмандарга каршы жүргүзүлүп жырткычтык зулум жана массалык кыргындарда бир четте көрүүчү болуп турууга ар бир момун мусулмандын ыйманы жол бербейт. Ошондуктан, ар бирибиз колубуздан келишинче куфрга каршы күрөш алып барышыбыз важиб. Аскерийлер аскердик жактан, саясатчылар саясий жактан, байлар материалдык жактан, уламалар ушул багыттар боюнча мусулмандарды багыттоо үчүн шаръий билдирүүлөр мене чыгуу аркылуу… ж.б.у.с ар бирибизге Аллах берген бардык мүмкүнчүлүктөрүбүздөн пайдаланып, куфрдун зулумдарына каршы кайраттуулук менен аракет кылуунун убагы келди. Болбосо, эки дүйнөдөгү жакшылыктарды колдон чыгарып жиберишибиз мүмкүн, мындан Аллах сактасын.
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Evidence was gathered from the latest reviews and up to date
authentic studies, particularly from potential cohorts and clinical trials, ultimately resulting in five
main topics of debate. First, AAS usage is briefly characterised
by its historical background, major physiological mechanisms,
and the most incessantly used AAS substances.
Second, knowledge on the prevalence of AAS-induced male infertility and sexual dysfunction are described.
Fourth, the potential treatments throughout and after
the AAS usage are presented, highlighting the chances of resolving male
infertility and sexual dysfunction. Fifth, future directions on this
matter are discussed, specializing in the
methodological robustness of scientific research. The evolving prevalence of anabolic androgenic steroids (AAS) abuse amongst nonathletes is alarming due to the known harm to
an individual’s health. Anabolic steroids are in a place to improve energy and muscle mass in some individuals when combined with
a proper diet and an intense training program.
By growing testosterone ranges, anabolic steroids can cut back the quantity of sperm
produced by the body. This dysfunction can be due to a lower in testosterone ranges and the direct effects of steroids on the blood vessels
and nerves involved in erections. Controversy continues to surround
prohormones in regard to their legality and effectiveness.
Observing the menace of testosterone misuse and abuse, current guidelines from AUA/ASRM jointly advise towards exogenous testosterone remedy in patients
in search of present or future fertility. It recommends hCG injections, SERMs, or AIs along
with TRT singly or together to mitigate opposed results on spermatogenesis.
For these with suboptimal fertility, an adjunct FSH remedy can be advised [35,36].
European Affiliation of Urology (EAU) additionally recommends towards TRT as
a therapy for male infertility. Various therapies
with hCG, or recombinant FSH (rFSH) for stimulating the endogenous
production of testosterone is recommended [37]. AAS use in the general population is linked to illicit drug use, prescription misuse, bodily training, and lower education ranges.
Lifetime prevalence in the U.S. is estimated at 0.9 % for males and 0.1 % for females,
higher amongst younger males (1.5–6 %) and females (0–2.four %).
For example, the number of AAS abusers are uncommon in Jap Asia but high in Brazil, Commonwealth countries,
Europe and North America (Pope, Wood, et al., 2014b).
In the quest for peak bodily performance and muscle mass, anabolic steroids have emerged as a preferred, yet
controversial, shortcut. These artificial substances, designed
to imitate the results of the male sex hormone testosterone, promise enhanced energy and stamina.
Use of anabolic steroids can lower the production of sperm to infertile levels and interrupt spermatogenesis (normal sperm development).
One notable exception is nandrolone, which is transformed into dihydronandrolone (DHN) by
5α-reductase. Nonetheless, whereas testosterone is converted into the stronger androgen DHT by
5α-reductase (21), the conversion of nandrolone into DHN yields an androgen with significantly decrease binding affinity for the
AR (77, 78). Thus, whereas testosterone’s actions could be
amplified in tissues expressing 5α-reductase, nandrolone’s actions may be diminished (21).
On the basis of this metabolism, the combination of a
5α-reductase inhibitor with nandrolone seems significantly misguided.
To manage this aspect impact, some AAS users resort to ancillary medicine for remedy.
This consists of use of the oral prescription drug isotretinoin by a small proportion of users (65, 67).
In many medical studies, multiple determinants have been found
to influence its end result. Longer length and better
doses of testosterone abuse increase the recovery time
of spermatogenesis after cessation of testosterone
use [24]. Pre-therapy small testicular volumes, aged age teams,
Asian ethnicity, high baseline serum FSH stage, and subfertility before initiation of TRT also influence restoration of fertility parameters [24–26].
The attract of anabolic steroids for enhancing bodily efficiency and muscle mass can not overshadow the significant risks they
pose, particularly regarding male fertility and the potential for delivery defects.
The evidence introduced underscores the detrimental results
these synthetic substances can have on sperm production, hormonal steadiness,
and general reproductive well being. There had been 12 cohort research, 5 case–control studies,
9 cross-sectional surveys and 6 case reviews.
Shokri et al. report a big increase within the fee of
apoptosis of spermatogenic cells after nandrolone administration, a rise
clearly amplified by bodily exercise [29]. Characteristically, extra anabolic
steroids present weaker AR bindings, and extra androgenic steroids strongly bind the AR, exerting a more potent effect.
The authors reported a mean consumption of three.1 product per
person and per cycle during the 5 to 10 weeks cycles, with doses
often being 5 to 29 times the physiological substitute doses
[8]. For males who expertise persistent infertility despite cessation of
steroid use and hormonal remedy, assisted reproductive applied sciences (ART) such as in vitro fertilization (IVF) or
intracytoplasmic sperm injection (ICSI) could additionally
be thought-about. These strategies can usually overcome the
obstacles to fertilization caused by compromised sperm high quality or amount.
By fostering a greater understanding of the connections between steroid use and fertility, we will try to
advertise knowledgeable decision-making and safeguard reproductive well being.
A Number Of research conclude that using anabolic steroids considerably decreased
quality sperm parameters. In one study of steroid-using bodybuilders,
researchers discovered that only 17.7% of men with a historical past of utilizing steroids had any morphologically normal sperm and solely 7% had
normal sperm counts. And another study that followed 20 male
bodybuilders using anabolic steroids over a 2-year interval discovered that decreased fertility
was one of the vital long-term antagonistic effects.
Testosterone, follicle-stimulating hormone (FSH), and
luteinizing hormone (LH), are three key hormones that drive
male fertility.
Nevertheless, there are some concerns regarding the connection between exercise supplements these designed for helping construct
muscle, and male fertility. The commonest unwanted side effects
of steroid use that happens in ladies have to
do with a lower in female elements and the
looks of male characteristics. Dealing with the reproductive consequences of steroids could be overwhelming and disheartening,
especially for many who are enthusiastic about bodybuilding.
However step one to overcoming that feeling
is understanding the means to protect your reproductive well being.
Absolutely, and pure supplements play a job on this context, highlighting the need for cautious consideration of all substances getting used.
It’s essential to analysis and perceive the potential unwanted aspect effects of any supplement.
In addition to lowering sperm counts, steroid abuse
can truly make the testicles shrink.
All Through this evaluation, we point out treatment choices for several unwanted aspect effects; these shouldn’t be considered strict recommendations, as they
are largely a mirrored image of how AAS customers self-medicate or what is thought from the literature.
It remains debatable whether or not physicians ought to medically goal
negative effects of AAS use. Obviously, discontinuing AAS
would be the preferred solution for just about every facet effect.
This could possibly be encouraged by affected person schooling on the attainable dangers and addressing psychological points that preserve AAS
use, corresponding to body dysmorphia and dependancy.
If the patient is nonetheless unwilling to stop, physicians may contemplate therapy to scale back
hurt, as is customary within the strategy and therapy of, for instance, people who
smoke and alcoholics. Throughout therapy with anabolic steroids, clinicians should periodically get hold of the
patient’s lipid profile, hepatic perform tests, hemoglobin, hematocrit (at three to six months,
then each year), PSA, and testosterone ranges.
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